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位置: 首页> 品牌> Sigma-Aldrich> Anti-WDR5 Antibody, clone 7B11

Anti-WDR5 Antibody, clone 7B11

品牌
Sigma-Aldrich
货号
MABE428
规格纯度
ascites fluid, clone 7B11, from mouse
价格
5180.56 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-WDR5 Antibody, clone 7B11
WD repeat-containing protein 5, BMP2-induced 3-kb gene protein
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

WD repeat-containing protein 5 (WDR5) or alternatively BMP2-induced 3kb gene protein, is encoded by the human gene named WDR5/BIG3 and is part of a family of WD-40 repeat proteins that appear to facilitate the formation of multi-protein complexes much like a sticky tape will bind a variety of components together. The WD repeat proteins are involved in a wide array of cellular functions and processes including cell cycle progression, homeobox gene activation, apoptosis, gene regulation and histone methylation. One of WDR5 best studied activities is as part of a multi-protein complex that facilitates the methylation of histones, particularly histone H3, through its interaction with MLL a histone methyltransferase. WDR5 is also expressed in developing bone cells including osteoblasts, chondrocytes, and marrow stromal cells and works to accelerate osteoblast differentiation and positively promotes Wnt signaling in developing bone tissues. EMD-Millipore’s Anti-WDR5 mouse monoclonal antibody has been tested in western blot using HeLa cell lysates.

免疫原

Purified recombinant fragment of human WDR5 expressed in E. Coli.

应用

Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors
Anti-WDR5 Antibody, clone 7B11 is a highly specific mouse monoclonal antibody & that targets WDR5 & has been tested in western blotting.

质量

Evaluated by Western Blotting in HeLa cell lysate.

Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected WDR5 in HeLa cell lysate.

Optimal working dilutions must be determined by end user.

目标描述

~40 kDa observed

外形

Mouse monoclonal IgG2b ascitic fluid containing up to 0.1% sodium azide.
Unpurified

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析说明

Control
HeLa cell lysate

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 ascites fluid
antibody product type primary antibodies
克隆 7B11, monoclonal
species reactivity human
technique(s) western blot: suitable
同位素/亚型 IgG2b
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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