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位置: 首页> 品牌> Sigma-Aldrich> Anti-WBP2 Antibody, clone 4C8H10

Anti-WBP2 Antibody, clone 4C8H10

品牌
Sigma-Aldrich
货号
MABS441
规格纯度
clone 4C8H10, from mouse
价格
5688.25 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-WBP2 Antibody, clone 4C8H10
WW domain-binding protein 2, WBP-2
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

WBP2 is a protein-protein interacting protein that binds to the WW domain of YAP1, WWP1 and WWP2 proteins. WW domain-containing proteins are found in most cells and play important roles in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. They are also upregulated in many cancers. WBP2 also interacts with the ubiquitin ligase proteins belonging to the NEDD4 family and appears to assist in the regulation of targeting proteins to proteasomes or lysosomes. Also in WBP2 knockout mice, the mice display abnormal brainstem and hearing development, indicating an important role in development as well.

免疫原

GST-tagged full length recombinant protein corresponding to Human WBP2.

应用

This Anti-WBP2 Antibody, clone 4C8H10 is validated for use in Western Blotting and Immunoprecipitation and Immunocytochemistry and Immunohistochemistry for the detection of WBP2.
Research Sub Category
Growth Factors & Receptors
Immunohistochemistry Analysis: A representative lot detected WBP2 in breast cancer tissue at 1.25 ug/ml
Immunocytochemistry Analysis: A representative lot detected WBP2 in transfected HeLa cell fixed with 4% paraformaldehyde at 20 ug/ml
Immunoprecipitation Analysis: A representative lot immunoprecipitated transfected V5-WBP2 from HeLa cell
Research Category
Signaling

Apoptosis & Cancer

质量

Evaluated by Western Blotting in MDA-MB-231 cell lysate.

Western Blotting Analysis: 2.0 ?g/mL of this antibody detected WBP2 in 10 ?g of MDA-MB-231 cell lysate.

目标描述

~ 37 kDa observed

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 4C8H10, monoclonal
species reactivity human
technique(s) immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
同位素/亚型 IgG1κ
NCBI登记号 NP_036610
UniProt登记号 Q969T9
运输 wet ice
Gene Information human ... WBP2(23558)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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