Anti-WAVE-1 Antibody, clone K91/36

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一般描述

Protein WAVE-1 (WAVE1) is also known as Wiskott-Aldrich syndrome protein (WASP) family member 1 (WASF1), verprolin homology domain-containing protein 1, or SCAR1. WAVE1 is a downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. WAVE1 binds actin and ARP2/3 complex. It binds the ARP2/3 complex through the C-terminal region and actin through verprolin homology (VPH) domain. WAVE1 is highly expressed in brain, with low expression in several other tissue.

免疫原

Linear peptide corresponding to human WAVE-1.

应用

Immunohistochemistry Analysis: A representative lot detected WAVE-1 in adult rat hippocampal CA1 tissue (Prof. J. Trimmer, University of California, Davis).
Research Category
Neuroscience
Detect WAVE1 using this mouse monoclonal antibody, Anti-WAVE-1 Antibody, clone K91/36 validated for use in western blotting & IHC.
Research Sub Category
Developmental Signaling

质量

Evaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected WAVE-1 in 10 µg of rat brain tissue lysate.

目标描述

~ 70 kDa observed

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Rat brain tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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