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位置: 首页> 品牌> Sigma-Aldrich> Anti-WAS protein family homolog 1 (CT) Antibody

Anti-WAS protein family homolog 1 (CT) Antibody

品牌
Sigma-Aldrich
货号
ABS72
包装型号
规格纯度
from rabbit
价格
4848.93 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-WAS protein family homolog 1 (CT) Antibody
WAS protein family homolog 1, family with sequence similarity 39, member E, CXYorf1-like protein on chromosome 2, Protein FAM39E
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Wiskott-Aldrich Syndrome Protein and SCAR Homolog (WASH) is a novel protein belonging to the WASP family, a group of nucleation promoting factors (NFPs) that activate a critical component in endocytosis, Arp 2/3. WASH contains three specific domains: a C-terminal VCA domain, a proline-rich domain, and an N terminal region containing two WASH homolog regions, WHD1 and WHD2. Although WASH has yet to be completely characterized, it is known to function as an NPF at the endosomal surface, where it is involved in the recruitment and subsequent activation of Arp2/3 in order to initiate actin polymerization. Therefore, WASH has a crucial role in endosomal sorting as a mediator of tubule fission resulting from Arp2/3 activation.

特异性

This antibody recognizes WAS protein family homolog 1 at the C-terminus.

免疫原

GST-tagged recombinant protein corresponding to human WAS protein family homolog 1 at the C-terminus.
Epitope: C-terminus

应用

Anti-WAS protein family homolog 1 (C-terminus) Antibody detects level of WAS protein family homolog 1 (C-terminus) & has been published & validated for use in WB.
Research Category
Signaling

质量

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1 ?g/mL of this antibody detected WAS protein family homolog 1 on 10 ?g of HeLa cell lysate.

目标描述

~ 60 kDa observed. The calculated molecular weight is 50 kDa

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
HeLa cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 purified antibody
antibody product type primary antibodies
克隆 polyclonal
species reactivity mouse, human
technique(s) western blot: suitable
同位素/亚型 IgG
NCBI登记号 NP_878908
UniProt登记号 A8K0Z3
运输 wet ice
Gene Information human ... WASH1(100287171)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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