半岛bd体育手机客户端 说明
一般描述
Vimentin is a class III intermediate filament protein (homopolymers) found in various non-epithelial cells including mesenchymal cells and fibroblasts. In many cells of mesenchymal origin, it is one of the most prominent phosphoproteins, especially during cell division when enhanced phosphorylation of vimentin corresponds with the reorganization of vimentin filaments.
特异性
Reacts with human mesenchymal cells and derived sarcomas. Reacts with an epitope of the cytoskeletal protein vimentin but unlike other vimentin antibodies, does not react with human lymphoid cells or derived malignancies. Reactive with endothelium, muscle, fibroblasts, melanocytes, peripheral nerve, sertoli cells, kidney mesangial cells and tubules, osteoblasts and periosteum, non-hematopoietic tumors of mesenchymal origin (all sarcomas), meningiomas and melanomas.
免疫原
Nuclei from adult human thymic biopsy specimens.
应用
Immunohistochemistry on B5 fixed, paraffin embedded tissue sections.
Anti-Vimentin Antibody, clone LN-6 detects level of Vimentin & has been published & validated for use in IH(P).
目标描述
57-60 kDa
外形
Liquid tissue culture supernatant containing 0.02% sodium azide.
分析说明
Control
Hyperplastic lymph nodes.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | culture supernatant |
antibody product type | primary antibodies |
克隆 | LN-6, monoclonal |
species reactivity | human, mouse |
manufacturer/tradename | Chemicon? |
technique(s) | immunohistochemistry: suitable (paraffin) |
同位素/亚型 | IgM |
NCBI登记号 | NM_003380.2 |
UniProt登记号 | P08670 |
运输 | dry ice |
Gene Information | human ... VIM(7431) |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich