Anti-UNC45B antibody produced in goat

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一般描述

UNC45B (unc-45 myosin chaperone B) codes for a myosin-specific chaperone. It is expressed in the heart and skeletal muscle tissue. It belongs to the UCS (UNC-45/CRO1/She4p) family of proteins. UNC-45 protein consists of an N-terminal tetratricopeptide repeat (TPR) domain along with the canonical UCS domain. It is located on human chromosome 17q12.

免疫原

Peptide with sequence RSDKLRQKIFKER, from the internal region of the protein sequence according to NP_775259.1; NP_001028748.1

生化/生理作用

UNC45B (unc-45 myosin chaperone B) helps in the assembly of type II myosins. It plays an important role in myoblast fusion and sarcomere organization. UNC45B plays a vital role in the progression of cardiomyopathy and in the breast cancer tumor growth.

特点和优势

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外形

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

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