Anti-TRIM5 alpha Antibody

半岛bd体育手机客户端 说明

一般描述

Tripartite motif-containing protein 5 (TRIM5), also known as RING finger protein 88 (RNF88), is a member of the TRIM/RBCC family defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region. TRIM5 has six alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain. TRIM5 isoform alpha is a retrovirus restriction factor, which mediates species-specific, early block to retrovirus infection.

特异性

This antibody recognizes the intermediate domain of TRIM5 alpha.

免疫原

KLH-conjugated linear peptide corresponding to the intermediate domain of human TRIM5 alpha.

应用

Detect Tripartite motif-containing protein 5 using this rabbit polyclonal antibody, Anti-TRIM5 alpha Antibody validated for use in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: 2 ?g/mL from a representative lot detected TRIM5 alpha in human stomach tissue.

Immunofluorescence Analysis: 10 ?g/mL from a representative lot detected TRIM5 alpha in human stomach cells.

质量

Evaluated by Western Blotting in human stomach, thymus, and uterus tissue lysates.

Western Blotting Analysis: 2 ?g/mL of this antibody detected TRIM5 alpha in 15 ?g of human stomach, thymus, and uterus tissue lysates.

目标描述

~55 kDa observed. Uniprot describes 6 isoforms ranging between ~30 kDa and ~56 kDa Uncharacterized bands may appear in some lysates.

外形

Antigen Affinity Purified

分析说明

Control
Human stomach, thymus, and uterus tissue lysates

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
纯化方式	affinity chromatography
species reactivity	human
technique(s)	immunofluorescence: suitable immunohistochemistry: suitable western blot: suitable
UniProt登记号	Q9C035
运输	wet ice

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable