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Anti-Transglutaminase-2 (C-terminal) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4200073
规格纯度
~1.5 mg/mL, affinity isolated antibody
价格
5045.46 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-Transglutaminase-2 (C-terminal) antibody produced in rabbit
Anti-TGC
Anti-G-alpha-h
Anti-C polypeptide, protein-glutamine-gamma-glutamyltransferase
Anti-TGM2
Anti-TG2
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Tranglutaminase-2 (also known as TGM2, TG2), is a widely expressed, multifunctional protein.

应用

Anti-Transglutaminase-2 (C-terminal) antibody produced in rabbit has been used in:

  • immunoblotting
  • immunoprecipitation
  • immunofluorescence
  • immunohistochemistry

生化/生理作用

Tranglutaminase-2 possesses enzymatic and GTPase activities, involved in multiple cell functions, including cell adhesion and cell signaling. TGM2 functions as a Ca2+-dependent enzyme capable of crosslinking both cytosolic and extracellular matrix proteins by catalyzing the formation of isopeptide bonds between lysine and glutamine residues. TGM2 is involved in the regulation of cell-matrix adhesion, cytoskeletal structure, cell migration and apoptosis. It is activated in response to tissue injury and plays an important role in wound healing and immune response. TGM2 is a major autoantigen in celiac disease and altered TGM2 expression or activity may be associated with Alzheimer′s disease, arteriosclerosis, type-2 diabetes and cancer metastasis in numerous forms of cancer.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen ~78 kDa
species reactivity human
包装 antibody small pack of 25 μL
浓度 ~1.5 mg/mL
technique(s) immunohistochemistry: 5-10 μg/mL using formalin-fixed and paraffin embedded human placenta
immunoprecipitation (IP): 15-30 μg using human placenta extracts
indirect immunofluorescence: 2-4 μg/mL using U87 cells
western blot: 1-2 μg/mL using U87 cell extracts
UniProt登记号 Q07283
运输 dry ice
储存温度 ?20℃
Gene Information human ... TGM2(7052)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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