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位置: 首页> 品牌> Sigma-Aldrich> Anti-Toso Antibody

Anti-Toso Antibody

品牌
Sigma-Aldrich
货号
ABC848
规格纯度
from rabbit, purified by affinity chromatography
价格
5854.74 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-Toso Antibody
Fas apoptotic inhibitory molecule 3, Regulator of Fas-induced apoptosis Toso, Toso
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Apoptosis is an important process by which normal tissue homeostasis and function are maintained. Toso (also known as Fas apoptotic inhibitory molecule 3, Regulator of Fas-induced apoptosis and FAIM3) is a novel regulator of Fas-induced apoptosis in lymphoid cells and when overexpressed in Jurkat cells as well as transgenic mice render these cells resistant to Fas-induced apoptosis but not to TRAIL-induced apoptosis. Furthermore, Toso was found to associate with FADD, suggesting that Toso functions by disrupting the formation of the death-inducing signaling complex.

免疫原

KLH-conjugated linear peptide corresponding to a 13 amino acid peptide near the C-terminus of human Toso.
Epitope: C-terminus

应用

Research Sub Category
Apoptosis - Additional
Anti-Toso Antibody is a highly specific rabbit polyclonal antibody, that targets Fas apoptotic inhibitory molecule 3 & has been tested in western blotting.
Research Category
Apoptosis & Cancer

质量

Evaluated by Western Blotting in human lung tissue lysate with and without blocking peptide.

Western Blotting Analysis: 1 μg/mL of this antibody detected Toso in human lung tissue lysate with and without blocking peptide.

目标描述

~60 kDa observed.
Despite its predicted molecular weight of 43 kDa, Toso often migrates at 60 kDa in western blots.
Uncharacterized bands may be observed in some lysate(s).

外形

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity human
technique(s) western blot: suitable
UniProt登记号 O60667
运输 wet ice
Gene Information human ... FAIM3(9214)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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