Anti-TNFRSF14 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

TNFRSF14 Antibody: Tumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-κB and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses.

免疫原

TNFRSF14 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human TNFRSF14.The immunogen is located within amino acids 20 - 70 of TNFRSF14.

应用

TNFRSF14 antibody can be used for the detection of TNFRSF14 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 1 μg/mL. For immunofluorescence start at 10 μg/mL.Antibody validated: Western Blot in mouse samples; Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

外形

Supplied in PBS containing 0.02% sodium azide.

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	liquid
species reactivity	mouse, human
浓度	1 mg/mL
technique(s)	immunofluorescence: suitable immunohistochemistry: suitable western blot: suitable
同位素/亚型	IgG
UniProt登记号	Q92956
运输	wet ice
储存温度	?20℃
Gene Information	human ... TNFRSF14(8764)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable