Anti-TM4SF1 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

Transmembrane 4 L6 family member 1 (TM4SF1) is a protein encoded by the TM4SF1 gene in humans. It is a cell surface antigen, which is highly expressed in lung, breast, colon and ovarian carcinomas. The TM4SF1 gene is localized on human chromosome 3q25.1.

免疫原

Antibody was raised against an 18 amino acid peptide near the amino terminus of human TM4SF1.

生化/生理作用

Transmembrane 4 L6 family member 1 (TM4SF1) has a novel function in androgen receptor (AR) signaling. Its mRNA expression is higher in prostate cancer tissues as compared to benign prostatic hyperplasia (BPH). It is found to contribute to prostate cancer cell metastasis. The TM4SF1 gene serves as a molecular organizer that interacts with membrane and cytoskeleton-associated proteins. It uniquely initiates the formation of nanopodia and facilitates cell polarization and migration. TM4SF1 also regulates tumor cell motility and invasiveness. It is abundant on the plasma membrane and on intracellular vesicles.

特点和优势

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联系

The action of this antibody can be blocked using blocking peptide SBP3500723.

外形

Supplied at 1 mg/mL in PBS with 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
分子量	22 kDa
species reactivity	human, rat, mouse
浓度	1 mg/mL
technique(s)	ELISA: suitable western blot: suitable
NCBI登记号	NP_055035
UniProt登记号	P30408
运输	wet ice
储存温度	?20℃
Gene Information	human ... TM4SF1(4071)

安全信息

储存分类代码	12 - Non Combustible Liquids
闪点(F)	Not applicable
闪点(C)	Not applicable