Anti-TIM-1 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

Hepatitis A virus cellular receptor 1 (HAVCR1) or T-cell immunoglobulin and mucin protein (TIM-1) is a type 1 transmembrane glycoprotein. The protein is found in the apical membrane of cells. It is expressed in the kidney, testis and activated CD4⁺T-cells. It possesses a six-cysteine immunoglobulin-like domain, a T/SP rich domain and two N-glycosylation sites. The TIM-1 gene is localized on human chromosome 5q33.2.

免疫原

TIM-1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human TIM-1.

应用

Anti-TIM-1 antibody produced in rabbit has been used in immunofluorescence.

生化/生理作用

Hepatitis A virus cellular receptor 1 (HAVCR1) regulates susceptibility to human immunodeficiency virus-1 (HIV-1) infection. It is upregulated in injured kidneys. HAVCR1 inhibits the activation of the Ga12 G-protein by blocking its association to GTP. Polymorphisms in the protein have been associated with immune dysfunction.

特点和优势

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联系

The action of this antibody can be blocked using blocking peptide SBP3500252.

外形

Supplied in PBS with 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	predicted mol wt 40 kDa
species reactivity	human, mouse
technique(s)	immunofluorescence: suitable immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable
NCBI登记号	NP_036338
UniProt登记号	Q96D42
运输	dry ice
储存温度	?20℃
Gene Information	human ... HAVCR1(26762)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable