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位置: 首页> 品牌> Sigma-Aldrich> Anti-TICAM1/TRIF (AB1) antibody produced in rabbit

Anti-TICAM1/TRIF (AB1) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB2900288
规格纯度
IgG fraction of antiserum, buffered aqueous solution
价格
5045.46 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti-TICAM1/TRIF (AB1) antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Toll like receptor adaptor molecule 1 (TICAM1) is ubiquitously expressed and possesses an N-terminal proline-rich domain, a TIR (Toll/interleukin-1 receptor) motif and a C-terminal proline-rich domain. The gene encoding this protein is localized on human chromosome 19p13.3.

免疫原

Synthetic peptide from human TICAM1 / TRIF.

生化/生理作用

Toll like receptor adaptor molecule 1 (TICAM1) plays a crucial role as an adaptor molecule and links toll-like receptor 3 (TLR3) to interferon-β (IFN-β) promoter activation. It is also involved in IFN-β production. TICAM-1 pathway has an essential role in host protection and innate immune responses against poliovirus (PV) infection. Mutations in the gene have been associated with the development of papillary thyroid cancer, follicular thyroid cancer and differentiated thyroid cancer.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 IgG fraction of antiserum
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
species reactivity human
technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable
UniProt登记号 Q8IUC6
运输 dry ice
储存温度 ?20℃
Gene Information human ... TICAM1(148022)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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