半岛bd体育手机客户端 说明
一般描述
Acyl-CoA thioesterase 13 (ACOT13), also known as thioesterase superfamily member 2 (THEM-2), is encoded by the gene mapped to human chromosome 6p22.3. The encoded protein has a molecular mass of ~15kDa with 140 amino acids. It is a member of the hotdog-domain thioesterase family. THEM2 is highly expressed in several tissues such as heart, kidney, liver and brown adipose tissue (BAT). It has been shown to be co-localized with β-tubulin on microtubules. At least two isoforms of THEM2 are known to exist.
免疫原
THEM2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human THEM2.
生化/生理作用
Acyl-CoA thioesterase 13 (ACOT13)/thioesterase superfamily member 2 (THEM-2) possesses thioesterase activity, with greater activity observed with longer chain acyl-CoAs such as myristoyl- and palmitoyl-CoA. THEM2 associates with StarD, a protein that plays a key role in fatty acid metabolism, and the addition of StarD to THEM2 increased its catalytic activity, suggesting that THEM2 plays a significant role in the metabolism of fatty acids.
特点和优势
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联系
The action of this antibody can be blocked using blocking peptide SBP3500070.
外形
Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
基本信息
NACRES | NA.41 |
半岛bd体育手机客户端 性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
species reactivity | rat, mouse, human |
technique(s) | immunofluorescence: suitable immunohistochemistry: suitable indirect ELISA: suitable western blot: suitable |
NCBI登记号 | NP_060943 |
UniProt登记号 | Q9NPJ3 |
运输 | dry ice |
储存温度 | ?20℃ |
Gene Information | human ... ACOT13(55856) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich