半岛bd体育手机客户端 说明
一般描述
Sulfonylurea receptor 1 (SUR1) is also called ATP-binding cassette sub-family C member 8, and is a member of the ABC transporter superfamily. SUR1 is a putative subunit of the beta-cell ATP-sensitive potassium channel (KATP) and functions as a regulator of ATP-sensitive K+ channels and insulin release.
特异性
This antibody recognizes the C-terminus of SUR1. Representative lot deteted Sur1 in crude brain membrane preparations
in SUR1 wild-type (WT) mouse cell lysate, and demonstrated a loss of signal in SUR1 knockout (KO) mouse cell lysate (Prof. J. Trimmer, University of California, Davis.).
免疫原
Recombinant protein corresponding to the C-terminus of rat SUR1.
应用
Anti-SUR1 Antibody, clone N289/16 is a highly specific mouse monoclonal antibody, that targets SUR & has been tested in western blotting & IHC.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SUR1 in human thalamus tissue.
质量
Evaluated by Western Blotting in mouse hypothalamus tissue lysate.
Western Blotting Analysis: 1.0 ?g/mL of this antibody detected SUR1 in 10 ?g of mouse hypothalamus tissue lysate.
目标描述
~ 180 kDa observed
外形
Protein G Purified
Format: Purified
分析说明
Control
Mouse hypothalamus tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | N289/16, monoclonal |
species reactivity | human, mouse |
species reactivity (predicted by homology) | rat (immunogen homology) |
technique(s) | immunohistochemistry: suitable western blot: suitable |
同位素/亚型 | IgG1κ |
NCBI登记号 | NP_037171 |
UniProt登记号 | Q09429 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich