Anti-STMN2 Antibody, clone L5/1

半岛bd体育手机客户端 说明

一般描述

Stathmin-like 2 (STMN2) protein is a phospho-protein and functions in microtubule dynamics and signal transduction. Studies show STMN2 plays a regulatory role in neuronal growth and thought to be involved in osteogenesis. Reduced levels, i.e. reduction in expression, have been associated with Down′s syndrome and Alzheimer′s disease. Data also suggests that STMN2 may play a role in modulating membrane interaction with the cytoskeleton during neurite outgrowth.

免疫原

Linear peptide corresponding to the C-terminus of rat STMN2.
Epitope: C-terminus

应用

Western Blotting Analysis: 0.5 ?g/mL from a representative lot detected STMN2 in 10 ?g of rat fetal brain (E16) tissue lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected STMN2 in rat hippocampus tissue.
Immunocytochemistry Analysis: A representative lot detected STMN2 in cultured hippocampal neurons (Prof. J. Trimmer, University of Califnornia, Davis.).
Detect STMN using this mouse monoclonal antibody, Anti-STMN2 Antibody, clone L5/1 validated for use in western blotting, IHC & ICC.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling

质量

Evaluated by Western Blotting in SH-SY-5Y cell lysate.

Western Blotting Analysis: 0.5 ?g/mL of this antibody detected STMN2 in 10 ?g of SH-SY-5Y cell lysate.

目标描述

~21 kDa observed

外形

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
抗体形式	purified antibody
antibody product type	primary antibodies
克隆	L5/1, monoclonal
species reactivity	human, rat
species reactivity (predicted by homology)	mouse (based on 100% sequence homology)
technique(s)	immunocytochemistry: suitable immunohistochemistry: suitable western blot: suitable
同位素/亚型	IgG2bκ
NCBI登记号	NP_445892
UniProt登记号	P21818
运输	wet ice

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable