Anti-SR-B2/LIMPII antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]

免疫原

A synthesized peptide derived from human SR-B2/SR-B2/LIMPII

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
antibody product type	primary antibodies
克隆	monoclonal
形式	liquid
species reactivity	mouse, human, rat
浓度	0.34 mg/mL
technique(s)	immunohistochemistry: 1:50-1:200 western blot: 1:500-1:2000
UniProt登记号	Q14108
运输	wet ice
储存温度	?20℃
Gene Information	human ... SCARB2(950)

安全信息

闪点(F)	Not applicable
闪点(C)	Not applicable