Anti-SnoN Antibody

半岛bd体育手机客户端 说明

一般描述

The Ski family of oncogenes includes Ski and Sno (Ski-related novel gene, or Ski-like). Ski family members are nuclear proteins that form homodimers and heterodimers, bind to DNA and function as transcriptional activators and repressors. The Ski proteins regulate TGF? induced gene-specific transcriptional activation by effectively repressing Smad activity and, thereby, inhibit TGF? induced cell growth and extracellular matrix production. Recently, SnoN has been shown to maintain pluripotency through selective repression of mesendodermal genes in human ES cells.

免疫原

KLH-conjugated linear peptide corresponding to amino acids 358-372 of human SnoN protein.

应用

Research Sub Category
Pluripotent & Early Differentiation
Research Category
Stem Cell Research
This Anti-SnoN Antibody is validated for use in Western Blotting and Immunocytochemistry and Immunohistochemistry for the detection of SnoN.
Immunohistochemical Analysis: A 1:50 dilution of this antibody detected SnoN in human skeletal muscle myocytes. Immunohistochemical Analysis: A 1:50 dilution of this antibody detected SnoN in human lung tissue.
Immunocytochemicaly Analysis: A 1:100 dilution of this antibody detected SnoN in H9 human embryonic stem cells.

质量

Evaluated by Western Blot in a human placenta tissue lysate. Western Blot Analysis: 1 μg/ml of this antibody detected SnoN in a 10μg of human placenta tissue lysate.

目标描述

~80 kDa observed

外形

Purified rabbit Polyclonal serum in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Antigen Affinity Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.75

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
纯化方式	affinity chromatography
species reactivity	human
technique(s)	immunocytochemistry: suitable immunohistochemistry: suitable western blot: suitable
NCBI登记号	NP_005405
UniProt登记号	P12757
运输	wet ice
Gene Information	human ... SKIL(6498)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable