Anti-SLC25A5 antibody produced in mouse

半岛bd体育手机客户端 说明

一般描述

This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene. Solute carrier family 25 member 5 (SLC25A5) is a mitochondrial protein, which promotes the exchange of ADP and ATP across the inner mitochondrial membrane. SLC25A5 is located on human chromosome Xq24. It is found mainly in proliferative and undifferentiated cells.

免疫原

SLC25A5 (AAH56160, 1 a.a. ~ 298 a.a) full-length human protein.

Sequence
MTDAAVSFAKDFLAGGVAAAISKTAVAPIERVKLLLQVQHASKQITADKQYKGIIDCVVRIPKEQGVLSFWRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKRTQFWRYFAGNLASGGAAGATSLCFVYPLDFARTRLAADVGKAGAEREFRGLGDCLVKIYKSDGIKGLYQGFNVSVQGIIIYRAAYFGIYDTAKGMLPDPKNTHIVISWMIAQTVTAVAGLTSYPFDTVRRRMMMQSGRKGTDIMYTGTLDCWRKIARDEGGKAFFKGAWSNVLRGMGGAFVLVLYDEIKKYT

生化/生理作用

Solute carrier family 25 member 5 (SLC25A5) is necessary for cellular energy metabolism. It transports ATP by glycolysis. SLC25A5 is an indicator of carcinogenesis. SLC25A5 is associated with non-syndromic intellectual disability. Silencing of this gene induces apoptosis and inhibits tumor growth.

外形

Solution in phosphate buffered saline, pH 7.4

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
偶联物	unconjugated
抗体形式	IgG fraction of antiserum
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	human
technique(s)	western blot: 1 μg/mL
UniProt登记号	P05141
运输	dry ice
储存温度	?20℃
Gene Information	human ... SLC25A5(292)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable