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位置: 首页> 品牌> Sigma-Aldrich> Anti-SIGLEC7 (D-siglec) (C-term) antibody produced in rabbit

Anti-SIGLEC7 (D-siglec) (C-term) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1300568
规格纯度
IgG fraction of antiserum, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-SIGLEC7 (D-siglec) (C-term) antibody produced in rabbit
Adhesion inhibitory recptor molecule-1
Anti-p75
Anti-AIRM-1
Anti-Siglec-7
Anti-QA79 membrane protein
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

SIGLECs are cell surface proteins of the Ig superfamily. Most SIGLECs have 1 or more cytoplasmic immune receptor tyrosine-based inhibitory motifs, or ITIMs. A large subgroup of SIGLECs share high homology with SIGLEC3 (CD33) and are localized to 19q13.4. The cDNA for the SLG gene encodes 2 variants, SLG-long (SLGL) and SLG-short (SLGS). The 595-amino acid SLGL protein contains a signal peptide and 2 V-set N-terminal Ig-like domains. The 477-amino acid SLGS protein has a weak signal sequence and, like most SIGLEC3-like SIGLECs, has only 1 V-set N-terminal Ig-like domain. Both variants contain 2 C2-set N-terminal Ig-like domains, a transmembrane domain, and a cytoplasmic tail with a putative ITIM and a putative SLAM-like tyrosine-based motif. The conserved arginine residue thought to be essential for sialic acid binding in other SIGLECs is replaced by a glutamine in SLGS and by a cysteine in SLGL. RT-PCR analysis detected high expression of both variants in spleen and small intestine, and SLGS was highly expressed in adrenal gland and SLGL was highly expressed in bone marrow. This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human D-siglec.

免疫原

SIGLEC7 (Q9NZQ1, )
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human D-siglec.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 IgG fraction of antiserum
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
species reactivity human
technique(s) indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI登记号 NP_057627
UniProt登记号 Q9Y286
运输 dry ice
储存温度 ?20℃
Gene Information human ... SIGLEC7(27036)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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