Anti-SERCA2 Antibody, clone IID8

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一般描述

The sarcoplasmic reticulum of striated muscle is a specialized intracellular membrane system that plays a critical role in the contraction and relaxation of muscle. The sarco/endoplasmic reticulum Ca2+ ATPases (SERCAs) mediate Ca2+ uptake into intracellular stores. SERCA mediated Ca2+ uptake induces and maintains muscular relaxation. SERCA1 is expressed in fast-twitch muscles, whereas SERCA2 is expressed in cardiac and slow-twitch muscles. SERCA2 plays an important part in regulating cardiac contractile function.

特异性

The antibody recognizes SERCA2.

免疫原

Purified canine cardiac sarcoplasmic reticulum.
Epitope: Unknown

应用

Research Category
Cell Structure
Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC (Eizema, 2007).
Research Sub Category
Cytoskeleton

Cytoskeletal Signaling
Anti-SERCA2 Antibody, clone IID8 is an antibody against SERCA2 for use in WB, IC, IH.

质量

Evaluated by Western Blot in HEK293 cell lysate.

Western Blot Analysis: 0.5 ?g/ml of the antibody detected SERCA2 in 10 ?g of HEK293 cell lysate.

目标描述

~ 110 kDa

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
HEK293 cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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