Anti-Septin 9 antibody, Rat monoclonal

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一般描述

Monoclonal Anti-Septin 9 (rat IgG2a isotype) is derived from the hybridoma 1A6C2 produced by the fusion of mouse myeloma cells and splenocytes from rat immunized with a synthetic peptide of corresponding to the N-terminus of rat Septin 9, conjugated to KLH. Septin 9 (SEPT9) is a member of the septin family (also designated MSF/eseptin/Sint1). This gene is mapped to human chromosome 17q25.

免疫原

synthetic peptide of corresponding to the N-terminus of rat Septin 9 conjugated to KLH

应用

Monoclonal Anti-Septin 9 has been used in:

• immunoblotting
• immunocytochemistry
• immunohistochemistry
• immunofluorescence

生化/生理作用

Septin 9 (SEPT9) has been implicated in tumorigenesis. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. In addition, SEPT9 is shown to be a DNA methylation-based biomarker, effectively discriminated colorectal cancer from normal specimens.

外形

Solution in 0.01M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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