半岛bd体育手机客户端 说明
一般描述
Selenoprotein K (SELK) is a selenoprotein that is localized at the endoplasmic reticulum, and highly expressed in the heart. SELK functions as an antioxidant that can bind to proteins such as the ER-associated degradation (ERAD) components p97 ATPase, Derlin-1 and -2, and SelS as well as proteins in the oligosaccharyltransferase complex. SELK may be involved in the Derlin-dependent ERAD of glycosylated misfolded proteins, is thought to be important in Ca2+ flux in immune cells, and is cleaved by m-calpain in resting macrophages.
免疫原
KLH-conjugated linear peptide corresponding to human SELK.
应用
Anti-SELK Antibody is a highly specific rabbit polyclonal antibody, that targets Selenoprotein K & has been tested in western blotting.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
质量
Evaluated by Western Blotting in A20 cell lysate.
Western Blotting Analysis: 2 ?g/mL of this antibody detected SELK in 15 ?g of A20 cell lysate.
目标描述
~10 kDa observed. Uncharacterized bands may appear in some lysate(s).
外形
Purified rabbit polyclonal PBS with up to 0.1% sodium azide.
Antigen Affinity Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
A20 cell lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
半岛bd体育手机客户端 性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | mouse |
species reactivity (predicted by homology) | human (immunogen homology) |
technique(s) | western blot: suitable |
UniProt登记号 | Q9Y6D0 |
运输 | wet ice |
Gene Information | human ... SELK(58515) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich