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位置: 首页> 品牌> Sigma-Aldrich> Anti-S100A9/MRP14 Antibody, clone 17

Anti-S100A9/MRP14 Antibody, clone 17

品牌
Sigma-Aldrich
货号
MABF276
规格纯度
clone 17, from mouse
价格
4848.93 *本价格含增值税费
促销
服务
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  • 增值税票
数量
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半岛bd体育手机客户端 名称:
Anti-S100A9/MRP14 Antibody, clone 17
Protein S100-A9, Calgranulin-B, Calprotectin L1H subunit, Leukocyte L1 complex heavy chain, Migration inhibitory factor-related protein 14, MRP-14, p14, S100 calcium-binding protein A9
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

S100A8, also known as Protein S100-A8, Calgranulin-A, Calprotectin L1L subunit, Cystic fibrosis antigen (CFAG), Leukocyte L1 complex light chain, Migration inhibitory factor related protein 8 (MRP-14), p8, S100 calcium binding protein A8, or Urinary stone protein band A, and encoded by the gene S100A8/CAGA/CFAG/MRP14, is an important protein that binds both zinc and calcium and plays an important role in the regulation of inflammatory processes and immune response. Found in complex with its partner S100A9, S100A8 facilitates chemotaxis, fatty acid trafficking, cytoskeleton reorganization, and NAPDPH oxidase activation and other intracellular activities, as well as a host of extracellular induced activities such as extracellular proinflammatory, antimicrobial, oxidant scavenging, and apoptotic activities . Additionally S100A8 can act as a potent autoimmunity amplifier and appears to augment various cancers and their spread when over expressed. S100A8 is widely expressed and used as biomarker in patients with inflammatory diseases and as a cancer marker in multiple forms of cancer.

免疫原

Recombinant protein corresponding to human S100A9/MRP14.

应用

Flow Cytometry Analysis: 0.5 ?g of this antibody from a representative lot detected S100A9/MRP14 in 1X10E6 peripheral blood mononuclear cells.
This Anti-S100A9/MRP14 Antibody, clone 17 is validated for use in Western Blotting and Flow Cytometry for the detection of S100A9/MRP14.
Research Sub Category
Immunoglobulins & Immunology
Research Category
Inflammation & Immunology

质量

Evaluated by Western Blotting in human spleen tissue lysate.

Western Blotting Analysis: 0.5 ?g/mL of this antibody detected S100A9/MRP14 in 10 ?g of human spleen tissue lysate.

目标描述

~13 kDa observed. Uncharacterized bands may be observed in some lysates.

外形

Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 17, monoclonal
species reactivity human
technique(s) flow cytometry: suitable
western blot: suitable
同位素/亚型 IgG1κ
NCBI登记号 NP_002956
UniProt登记号 P06702
运输 wet ice
Gene Information human ... S100A9(6280)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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