Anti-RCC1 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis (PubMed:1944575, PubMed:17435751, PubMed:20668449, PubMed:22215983, PubMed:11336674). Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis (PubMed:12194828, PubMed:17435751, PubMed:22215983). Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import (PubMed:22215983). Involved in the regulation of onset of chromosome condensation in the S phase (PubMed:3678831). Binds both to the nucleosomes and double-stranded DNA (PubMed:17435751, PubMed:18762580).

免疫原

A synthesized peptide derived from human RCC1

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
antibody product type	primary antibodies
克隆	monoclonal
形式	liquid
species reactivity	rat, mouse, human
浓度	0.51 mg/mL
technique(s)	immunohistochemistry: 1:50-1:100 immunohistochemistry: 1:50-1:200 western blot: 1:500-1:2000
UniProt登记号	P18754
运输	wet ice
储存温度	?20℃
Gene Information	human ... RCC1(1104)

安全信息

闪点(F)	Not applicable
闪点(C)	Not applicable