您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 品牌> Sigma-Aldrich> Anti-Rab27B Antibody

Anti-Rab27B Antibody

品牌
Sigma-Aldrich
货号
ABS1026
规格纯度
serum, from rabbit
价格
5520.38 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-Rab27B Antibody
Ras-related protein Rab-27B, C25KG
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

RAB27B, also known as C25KG, is a member of the Rab GTPase superfamily. RAB27B acts as a lipid anchoring protein that is prenylated and works in vesicular fusion and protein trafficking within cells. The protein is most highly expressed in testis but can be expressed in other cell types as well. Because Rab27B is widely expressed in various tissues together with Rab27A and RAB27B has been found to have the ability to bind all of the Rab27A effectors that have been tested, Rab27A and Rab27B were initially thought to function redundantly by sharing common Rab27 effectors. However, recent evidence has indicated that by interacting with different Rab27 effectors Rab27A and Rab27B play different roles in special types of secretion (e.g. exosome secretion and mast cell secretion) even within the same cell type. Rab27B is particularly important for regulating protein secretion by pancreatic acinar cells, for instance.

免疫原

GST-tagged recombinant protein corresponding to human Rab27B.

应用

Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected Rab27B in 10 ?g of C2C12, mouse brain, and PC3 lysate.
Western Blotting Analysis: A representative lot detected Rab27B in rat parotid gland lysate (Imai, A., et al. (2004). Journal of Cell Science. 117:1945-1953).
Immunoprecipitation Analysis: A representative lot immunoprecipitated Rab27B in flg-Rab27B (Imai, A., et al. (2004). Journal of Cell Science. 117:1945-1953).
Immunohistochemistry Analysis: A representative lot detected Rab27B in rat parotid acinar cells (Imai, A., et al. (2004). Journal of Cell Science. 117:1945-1953).
Research Category
Signaling
Research Sub Category
Signaling Neuroscience
This Anti-Rab27B Antibody is validated for use in Western Blotting and Immunoprecipitation and Immunohistochemistry for the detection of Rab27B.

质量

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected Rab27B in 10 ?g of mouse brain tissue lysate.

目标描述

~27 kDa observed. Uncharacterized band(s) may appear in some lysates.

外形

Rabbit polyclonal serum with 0.05% sodium azide.
Unpurified

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 serum
antibody product type primary antibodies
克隆 polyclonal
species reactivity rat, mouse, human
technique(s) immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
NCBI登记号 NP_004154.2
UniProt登记号 O00194
运输 wet ice
Gene Information human ... RAB27B(5874)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1

Sigma-Aldrich

推荐半岛bd体育手机客户端
Baidu
map