Anti-Rab21 Antibody

半岛bd体育手机客户端 说明

一般描述

RAB21 is a member of the small GTPase superfamily that is critically important in the recycling of integrin protein receptor complexes and their internalization. Thus, RAB21 is important in cell adhesion and migration of cells, as well as the proper completing of cytokinesis which requires particular care with adherent cells to coordinate the release and recycling of integrin and their release from the ECM matrix during cytokinesis. RAB21 is primarily a cytoplasmic or cytoplasmic organelle localized protein and its precise location will vary with cell cycle and cell division phases. RAB21 is widely expressed particularly in cells in the gut and capillaries where cell division and cell morphological changes are common.

免疫原

GST-tagged recombinant protein corresponding to Mouse Rab21.

应用

Research Sub Category
Apoptosis - Additional
Western Blot Analysis: A 1:1000 dilution of a representative lot of this antibody detected Rab21 in A431, C2C12, HEK293, HeLa, HepG2, Jurkat, L6, Mouse brain, NIH/3T3, PC12, PC3, and RAW264.7 cell lysates. This antibody did not detect Rab21 in Human placenta or Huvec cell lysates.

Western Blot Analysis: A representative lot of this antibody detected Rab21 in melanocyte membrane compartment lysate (Ohbayashi et al., (2012) Mol Biol Cell. 23(4):669-678).
This Anti-Rab21 Antibody is validated for use in Western Blotting for the detection of Rab21.
Research Category
Apoptosis & Cancer

质量

Evaluated by Western Blotting in PC12 cell lysate.

Western Blotting Analysis: A 1:1000 dilution of this antibody detected Rab21 in 10 ?g of PC12 cell lysate.

目标描述

~24 kDa observed.
Uncharacterized bands may be obeserved in some lysates.

外形

Purified rabbit Polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Antigen Affinity Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
纯化方式	affinity chromatography
species reactivity	human, rat, mouse
technique(s)	western blot: suitable
NCBI登记号	NP_055814
UniProt登记号	Q9UL25
运输	wet ice
Gene Information	human ... RAB21(23011)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable