Anti-QKI-5 Antibody, clone N195A/16

半岛bd体育手机客户端 说明

一般描述

QKI (Quaking) is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability, and protein translation. It is regulated by alternative splicing. There are at least 6 known isoforms, and QKI-5 refers to isoforms 1, which is the ′canonical′ sequence, consisting of 341 amino acids.

特异性

This antibody does not cross react with QKI-6, QKI-7, and QKI-7b. This antibody may cross react with other STAR proteins containing similar nuclear localization signals (Prof. J. Trimmer, Univerisity of California, Davis.).

免疫原

Linear peptide corresponding to human QKI-5.

应用

Detect QKI using this mouse monoclonal antibody, Anti-QKI-5 Antibody, clone N195A/16 validated for use in IHC & western blotting.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected QKI-5 in human cerebellum and thalamus tissues, and in rat hippocampus tissue.

Western Blotting Analysis: A representative lot detected QKI-5 in COS cell lysates transiently transfected with Flag-tagged QKI-5 (Prof. J. Trimmer, University of California, Davis.).

质量

Evaluated by Immunohistochemistry in rat cerebellum tissue.

Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected QKI-5 in rat cerebellum tissue.

目标描述

45 kDa calculated

外形

Protein G Purified
Format: Purified

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	N195A/16, monoclonal
species reactivity	human, rat
species reactivity (predicted by homology)	mouse (based on 100% sequence homology)
technique(s)	immunohistochemistry: suitable western blot: suitable
同位素/亚型	IgG1κ
NCBI登记号	NP_006766
UniProt登记号	Q96PU8
运输	wet ice
Gene Information	human ... QKI(9444)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable