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Anti-PYCARD, (N-terminal) antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1407378
规格纯度
purified immunoglobulin, buffered aqueous solution
价格
4618.16 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-PYCARD, (N-terminal) antibody produced in mouse
MGC10332
TMS
TMS-1
CARD5
TMS1
ASC
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)

免疫原

PYCARD (AAH13569, 1 a.a. ~ 149 a.a) full-length human protein.

Sequence
MDALDLTDKLVSFYLETYGAELTANVLRDMGLQEMAGQLQAATHQGSGAAPAGIQAPPQSAAKPGLHFIDQHRAALIARVTNVEWLLDALYGKVLTDEQYQAVRAEPTNPSKMRKLFNFTPAWNWTCKDLLLQALRESQSYLVEDLERS

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen ~16.5 kDa
species reactivity human
technique(s) western blot: 1 μg/mL
NCBI登记号 BC013569
UniProt登记号 Q9ULZ3
运输 dry ice
储存温度 ?20℃
Gene Information human ... PYCARD(29108)

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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