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Anti-PTPN11 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700078
包装型号
规格纯度
价格
4713.83 *本价格含增值税费
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服务
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数量
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半岛bd体育手机客户端 名称:
Anti-PTPN11 antibody produced in rabbit
SHP2
PTPN11
BPTP3
JMML
CFC
PTP2C
SH-PTP2
PTP-1D
METCDS
NS1
SH-PTP3
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. Two transcript variants encoding different isoforms have been found for this gene.

免疫原

Recombinant fusion protein containing a sequence corresponding to amino acids 1-460 of human PTPN11 (NP_002825.3).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 52
68
species reactivity mouse, human, rat
浓度 0.71 mg/ml
technique(s) immunofluorescence: 1:50-1:200
western blot: 1:500-1:2000
UniProt登记号 Q06124
运输 wet ice
储存温度 ?20℃
Gene Information human ... PTPN11(5781)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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