Anti-PTPN21 (C-terminal) antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.

免疫原

Synthetic peptide directed towards the C-terminal region of Human PTPN21

序列

Synthetic peptide located within the following region: FWQMVWEQGIAIIAMVTAEEEGGREKSFRYWPRLGSRHNTVTYGRFKITT

外形

Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

半岛bd体育手机客户端 性质

生物来源	rabbit
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	133 kDa
species reactivity (predicted by homology)	bovine, mouse, horse, rabbit, rat, canine, guinea pig, human
浓度	0.5 mg/mL
technique(s)	western blot: 1 μg/mL
NCBI登记号	NM_007039
运输	wet ice
储存温度	?20℃
Gene Information	human ... PTPN21(57396)

安全信息

储存分类代码	10 - Combustible liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable