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位置: 首页> 品牌> Sigma-Aldrich> 5′-AMP-activated protein kinase subunit γ-2

Anti-PRKAG2 antibody produced in rabbit

5′-AMP-activated protein kinase subunit γ-2

品牌
Sigma-Aldrich
货号
SAB4502130
规格纯度
affinity isolated antibody
价格
5045.46 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-PRKAG2 antibody produced in rabbit
AMPK γ-2 chain
AAKG2
5′-AMP-activated protein kinase subunit γ-2
AMPK γ2
H91620p
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

PRKAG2 (protein kinase, AMP-activated, γ2 non-catalytic subunit) is a non-catalytic regulatory subunit of heterotrimeric AMP-activated protein kinase (AMPK), involved in the energy metabolism. It is predominantly present in all subcellular fractions, including the nuclei.
Anti-PRKAG2 Antibody detects endogenous levels of total PRKAG2 protein.

免疫原

The antiserum was produced against synthesized peptide derived from human PRKAG2.

Immunogen Range:1-50

应用

Anti-PRKAG2, N-Terminal antibody produced in rabbit is suitable for immunohistochemistry and indirect immunofluorescence.

生化/生理作用

PRKAG2 (protein kinase, AMP-activated, γ2 non-catalytic subunit) acts as a sensor of cellular energy status that is controlled by AMP (positively) and ATP (negatively). In normal state CBS domains from AMP-activated protein kinase can bind AMP, ATP, or S-adenosyl methionine. But in mutated condition, it cannot bind. As a result, it leads to hereditary diseases. Its major activity is involved in the regulation of energy homeostasis. It plays an important role in correcting of cell division and chromosome segregation during mitosis. Mutation in PRKAG2 causes Wolff-Parkinson-White (WPW) syndrome, a rare autosomal dominant inheritance disease.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen 63 kDa
species reactivity mouse, human
浓度 ~1 mg/mL
technique(s) ELISA: 1:20000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
NCBI登记号 Q9UGJ0
UniProt登记号 Q9UGJ0
运输 wet ice
储存温度 ?20℃
Gene Information human ... PRKAG2(51422)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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