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位置: 首页> 品牌> Sigma-Aldrich> Anti-PNAS4 antibody produced in rabbit

Anti-PNAS4 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB3500052
规格纯度
affinity isolated antibody, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-PNAS4 antibody produced in rabbit
Anti-PPPDE peptidase domain containing 1
Anti-FAM152A
Anti-CGI-146
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

PNAS4 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PNAS4.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

PNAS4 is a highly conserved protein that shares high homology from plants to animals. It was initially identified as a putative apoptosis-related protein in the human acute promyelocytic leukemia cell line NB4. PNAS4 is activated during the early response to DNA damage and can inhibit proliferation via apoptosis when overexpressed in some tumor cells such as U2OS, SKOV3, and A549. PNAS4 inhibits tumor cell proliferation through the following mechanisms: (i) overexpression of PNAS4 causes S phase arrest by regulating the expression of cell cycle-related proteins and (ii) PNAS4 induces apoptosis through the mitochondrial apoptosis pathway. Recent evidence has shown that PNAS4 may be involved in the genesis of some cancers and could be a potential candidate for lung cancer therapy alone or in combination with gemcitabine. At least two isoforms of PNAS4 are known to exist.

联系

The action of this antibody can be blocked using blocking peptide SBP3500052.

外形

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
species reactivity mouse, rat, human
technique(s) indirect ELISA: suitable
western blot: suitable
NCBI登记号 NP_057160
UniProt登记号 Q9BSY9
运输 dry ice
储存温度 ?20℃
Gene Information human ... PPPDE1(51029)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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