Anti-PLK2 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

Polo-like kinases 2 (PLK2) is a member of the serine-threonine kinases family. The PLK2 gene is mapped to human chromosome 5q11.2. PLK2 comprises a C-terminal polo-box domain (PBD) devoid of catalytic activity and an N-terminal kinase domain.
Anti-PLK2 Antibody detects endogenous levels of total PLK2 protein.

免疫原

The antiserum was produced against synthesized peptide derived from human PLK2.

Immunogen Range:291-340

应用

Anti-PLK2 antibody produced in rabbit has been used in western blotting(1:1000) (1:5000)

生化/生理作用

Polo-like kinase 2 (PLK2) participates in regulating centriole duplication, cell death, and cell cycle. It also mediates the spine-associated RapGAP (SPAR) degradation via the ubiquitin-proteasome pathway, thereby regulating synaptic plasticity. Mutations in the PLK2 gene are observed in colorectal cancers. The PLK2 gene knockdown leads to defects in centriole duplication.

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
分子量	antigen 78 kDa
species reactivity	mouse, rat, human
浓度	~1 mg/mL
technique(s)	ELISA: 1:40000 western blot: 1:500-1:1000
NCBI登记号	Q9NYY3
UniProt登记号	Q9NYY3
运输	wet ice
储存温度	?20℃
Gene Information	human ... PLK2(10769)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable