半岛bd体育手机客户端 说明
一般描述
Pinch-1 (Particularly interesting new Cys-His protein 1) is also known as LIM and senescent cell antigen-like-containing domain protein 1 (LIMS1). Pinch-1 is expressed in most tissues except for brain. Pinch-1 is an adhesion protein and is part of the ILK-PINCH complex that is involved in integrin and growth factor signaling by coupling surface receptors to downstream signaling molecules related to the regulation of cell survival, cell proliferation and cell differentiation.
免疫原
KLH-conjugated linear peptide corresponding to human Pinch-1.
应用
Research Category
Cell Structure
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Pinch-1 in human renal tubules and mouse renal tubules tissue.
Research Sub Category
Adhesion (CAMs)
Anti-Pinch-1 Antibody, clone 9D2.1 is a highly specific mouse monoclonal antibody, that targets Pinch-1 & has been tested in western blotting & IHC.
质量
Evaluated by Western Blotting in human heart tissue lysate.
Western Blotting Analysis: 0.5 ?g/mL of this antibody detected Pinch-1 in 10 ?g of human heart tissue lysate.
目标描述
~40 kDa observed. Uniprot describes 4 isoforms produced by alternative splicing at ~38 kDa, ~44 kDa, ~37 kDa, and ~42 kDa
外形
Purified by Ion-Exchange Chromatography
Format: Purified
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Human heart tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 9D2.1, monoclonal |
species reactivity | mouse, human |
technique(s) | immunohistochemistry: suitable western blot: suitable |
同位素/亚型 | IgMκ |
NCBI登记号 | NP_001180411 |
UniProt登记号 | P48059 |
运输 | wet ice |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich