半岛bd体育手机客户端 说明
一般描述
This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene.
免疫原
A phospho specific peptide corresponding to residues surrounding Y493 of human ZAP70
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
半岛bd体育手机客户端 性质
生物来源 | rabbit |
质量水平 | 100 |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | liquid |
species reactivity | human |
浓度 | 2.66 mg/mL |
technique(s) | western blot: 1:500-1:2000 |
UniProt登记号 | P43403 |
运输 | wet ice |
储存温度 | ?20℃ |
Gene Information | human ... ZAP70(7535) |
安全信息
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich