Anti-Phospho-STAT5A-Y694 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene.

免疫原

A synthetic phosphorylated peptide around Y694 of human STAT5A (NP_001275647.1).

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
antibody product type	primary antibodies
克隆	polyclonal
形式	liquid
species reactivity	rat, human, mouse
浓度	1.93 mg/mL
technique(s)	immunohistochemistry: 1:50-1:200 western blot: 1:500-1:2000
UniProt登记号	P42229
运输	wet ice
储存温度	?20℃
Gene Information	human ... STAT5A(6776)

安全信息

闪点(F)	Not applicable
闪点(C)	Not applicable