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位置: 首页> 品牌> Sigma-Aldrich> Anti-Phospho-STAT5-Y694 antibody produced in rabbit

Anti-Phospho-STAT5-Y694 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700522
包装型号
规格纯度
价格
4713.83 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-Phospho-STAT5-Y694 antibody produced in rabbit
stat5a/stat5b
STAT5
MGF
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene.

免疫原

A phospho specific peptide corresponding to residues surrounding Y694 of human STAT5.

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 90
species reactivity rat, mouse, human
浓度 2.75 mg/ml
technique(s) immunohistochemistry: 1:100-1:200
western blot: 1:500-1:2000
UniProt登记号 P42229
P51692
运输 wet ice
储存温度 ?20℃
Gene Information human ... STAT5(6776)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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