半岛bd体育手机客户端 说明
一般描述
The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
免疫原
A phospho specific peptide corresponding to residues surrounding Y693 of human STAT4
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
半岛bd体育手机客户端 性质
生物来源 | rabbit |
质量水平 | 100 |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | liquid |
species reactivity | rat, human, mouse |
浓度 | 0.976 mg/mL |
technique(s) | immunohistochemistry: 1:50-1:200 western blot: 1:500-1:2000 |
UniProt登记号 | Q14765 |
运输 | wet ice |
储存温度 | ?20℃ |
Gene Information | human ... STAT4(6775) |
安全信息
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich