Anti-Phospho-STAT3-S727 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]

免疫原

A synthesized peptide derived from human Phospho-Phospho-STAT3-S727 (S727).

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
antibody product type	primary antibodies
克隆	monoclonal
形式	liquid
species reactivity	human
浓度	1.48 mg/mL
technique(s)	western blot: 1:500-1:2000
UniProt登记号	P40763
运输	wet ice
储存温度	?20℃
Gene Information	human ... STAT3(6774)

安全信息

闪点(F)	Not applicable
闪点(C)	Not applicable