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位置: 首页> 品牌> Sigma-Aldrich> Anti-Phospho-SMC1A-S957 antibody produced in rabbit

Anti-Phospho-SMC1A-S957 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700325
包装型号
规格纯度
价格
4713.83 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-Phospho-SMC1A-S957 antibody produced in rabbit
DXS423E
SMCB
SMC1A
CDLS2
SMC1
SMC1alpha
SMC1L1
SB1.8
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.

免疫原

A synthetic phosphorylated peptide around S957 of human SMC1A (NP_006297.2).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 143
species reactivity mouse, rat, human
浓度 0.96 mg/ml
technique(s) immunofluorescence: 1:20-1:100
immunohistochemistry: 1:50-1:200
immunoprecipitation (IP): 1:50-1:100
western blot: 1:500-1:2000
UniProt登记号 Q14683
运输 wet ice
储存温度 ?20℃
Gene Information human ... SMC1A(8243)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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