Anti-Phospho-Raf1-S259 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

This gene is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration. Mutations in this gene are associated with Noonan syndrome 5 and LEOPARD syndrome 2. [provided by RefSeq, Jul 2008]

免疫原

A phospho specific peptide corresponding to residues surrounding S259 of human Phospho-Raf1-S259

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
antibody product type	primary antibodies
克隆	monoclonal
形式	liquid
species reactivity	mouse, human
浓度	1.25 mg/mL
technique(s)	western blot: 1:500-1:2000
UniProt登记号	P04049
运输	wet ice
储存温度	?20℃
Gene Information	human ... RAF1(5894)

安全信息

闪点(F)	Not applicable
闪点(C)	Not applicable