Anti-Phospho-PTK2B-Y402 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration, nicotinic acetylcholine receptor activation, membrane depolarization, or protein kinase C activation. This protein has been shown to bind CRK-associated substrate, nephrocystin, GTPase regulator associated with FAK, and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene.

免疫原

A phospho specific peptide corresponding to residues surrounding Y402 of human PTK2B

外形

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
antibody product type	primary antibodies
克隆	polyclonal
形式	liquid
species reactivity	human, mouse
浓度	0.755 mg/mL
technique(s)	western blot: 1:500-1:2000
UniProt登记号	Q14289
运输	wet ice
储存温度	?20℃
Gene Information	human ... PTK2B(2185)

安全信息

闪点(F)	Not applicable
闪点(C)	Not applicable