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位置: 首页> 品牌> Sigma-Aldrich> Anti-Phospho-PAK4/PAK5/PAK6-S474/S560/S602 antibody produced in rabbit

Anti-Phospho-PAK4/PAK5/PAK6-S474/S560/S602 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5701871
包装型号
规格纯度
价格
5406.77 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti-Phospho-PAK4/PAK5/PAK6-S474/S560/S602 antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

免疫原

A phospho specific peptide corresponding to residues surrounding S474 of human PAK4

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
antibody product type primary antibodies
克隆 monoclonal
形式 liquid
species reactivity mouse, human
浓度 1.65 mg/mL
technique(s) western blot: 1:500-1:2000
UniProt登记号 O96013(PAK4-Antigen),Q9P286(PAK5),Q9NQU5(PAK6)
运输 wet ice
储存温度 ?20℃

安全信息

闪点(F) Not applicable
闪点(C) Not applicable

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