Anti-Phospho-NFKB1-S337 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed.

免疫原

A phospho specific peptide corresponding to residues surrounding S337 of human NFKB1

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
antibody product type	primary antibodies
克隆	polyclonal
形式	liquid
species reactivity	mouse, rat, human
浓度	1.12 mg/mL
technique(s)	western blot: 1:500-1:2000
UniProt登记号	P19838
运输	wet ice
储存温度	?20℃
Gene Information	human ... NFKB1(4790)

安全信息

闪点(F)	Not applicable
闪点(C)	Not applicable