半岛bd体育手机客户端 说明
免疫原
Peptide sequence around phosphorylation site of serine 927 (C-D-S(p)-G-V), according to the protein NFKB1.
特点和优势
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目标描述
NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.
外形
Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol
基本信息
MDL编号 | MFCD00802846 |
NACRES | NA.41 |
半岛bd体育手机客户端 性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | ~120 kDa ~50 kDa |
species reactivity | mouse, rat, human |
浓度 | 1 mg/mL |
technique(s) | immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100 indirect immunofluorescence: 1:100-1:200 western blot: 1:500-1:1000 |
同位素/亚型 | IgG |
免疫原序列 | (C-D-SP-G-V) |
NCBI登记号 | NP_001158884.1 |
UniProt登记号 | P19838 |
运输 | wet ice |
储存温度 | ?20℃ |
Gene Information | human ... NFKB1(4790) |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich