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位置: 首页> 品牌> Sigma-Aldrich> Anti-Phospho-NEDD4L-S448 antibody produced in rabbit

Anti-Phospho-NEDD4L-S448 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700504
包装型号
规格纯度
价格
4713.83 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-Phospho-NEDD4L-S448 antibody produced in rabbit
RSP5
NEDD4.2
NEDD4-2
NEDD4L
PVNH7
hNedd4-2
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein mediates the ubiquitination of multiple target substrates and plays a critical role in epithelial sodium transport by regulating the cell surface expression of the epithelial sodium channel, ENaC. Single nucleotide polymorphisms in this gene may be associated with essential hypertension. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

免疫原

A synthetic phosphorylated peptide around S448 of human NEDD4L (NP_001138439.1).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 96-111
species reactivity human, rat, mouse
浓度 1.74 mg/ml
technique(s) western blot: 1:500-1:2000
UniProt登记号 Q96PU5
运输 wet ice
储存温度 ?20℃
Gene Information human ... NEDD4L(23327)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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