Anti-Phospho-MAP3K5-S967 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.

免疫原

A phospho specific peptide corresponding to residues surrounding S967 of human MAP3K5

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
antibody product type	primary antibodies
克隆	polyclonal
形式	liquid
species reactivity	human, mouse
浓度	0.925 mg/mL
technique(s)	western blot: 1:500-1:2000
UniProt登记号	Q99683
运输	wet ice
储存温度	?20℃
Gene Information	human ... MAP3K5(4217)

安全信息

闪点(F)	Not applicable
闪点(C)	Not applicable