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位置: 首页> 品牌> Sigma-Aldrich> Anti-Phospho-MAP3K5-S1033 antibody produced in rabbit

Anti-Phospho-MAP3K5-S1033 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700307
包装型号
规格纯度
价格
4314.62 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti-Phospho-MAP3K5-S1033 antibody produced in rabbit
MAPKKK5
MAP3K5
MEKK5
ASK1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.

免疫原

A phospho specific peptide corresponding to residues surrounding S1033 of human MAP3K5

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 154
69
species reactivity human, rat, mouse
浓度 0.26 mg/ml
technique(s) western blot: 1:500-1:2000
UniProt登记号 Q99683
运输 wet ice
储存温度 ?20℃
Gene Information human ... MAP3K5(4217)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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