半岛bd体育手机客户端 说明
一般描述
This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants.
免疫原
A synthetic phosphorylated peptide around T261 of human MAP2K4 (NP_003001.1).
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
半岛bd体育手机客户端 性质
生物来源 | rabbit |
质量水平 | 100 |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | liquid |
species reactivity | mouse, rat, human |
浓度 | 2.59 mg/mL |
technique(s) | immunohistochemistry: 1:50-1:100 immunohistochemistry: 1:50-1:200 western blot: 1:500-1:1000 |
UniProt登记号 | P45985 |
运输 | wet ice |
储存温度 | ?20℃ |
Gene Information | human ... MAP2K4(6416) |
安全信息
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich